The couple, who have been dating since 2005, were allegedly involved in an argument that saw Angelina throw a glass of red wine over Pitt after he accused her of being "immature" during a vacation in France, World Entertainment News Network reported.
Reports also say the pair has discussed custody plans to be put in place for kids Maddox, Zahara, Pax and Shiloh if they break up.
A source tells Life & Style magazine: "Angie was cursing him and ending up throwing a glass of wine in his face. Brad was absolutely disgusted by her behavior.
"Brad's had enough of doing what Angie wants to do and following her around the globe."
